Includes both UMN and LMN symptoms, which condition would exhibit this feature?

Amyotrophic Lateral Sclerosis (ALS) is characterized by the presence of both upper motor neuron (UMN) and lower motor neuron (LMN) symptoms. In ALS, the degeneration of motor neurons occurs in both the brain (which gives rise to UMN symptoms) and the spinal cord (which leads to LMN symptoms).

UMN symptoms can manifest as spasticity, hyperreflexia, and weakness due to the loss of control from the brain's motor cortex. On the other hand, LMN symptoms include muscle wasting, fasciculations, and weakness resulting from the damage to the motor neurons in the spinal cord and brainstem. The combination of these symptoms is a hallmark of ALS, distinguishing it from conditions that primarily affect either UMN or LMN pathways alone.

In contrast, Alzheimer's disease primarily affects cognitive function and is not characterized by motor neuron involvement. Cerebral Palsy generally results from non-progressive damage to the brain during development and often manifests with UMN symptoms such as spasticity but lacks direct LMN involvement. Chronic Fatigue Syndrome is marked by debilitating fatigue and does not typically present with the specific motor neuron symptoms associated with UMN or LMN dysfunction. Thus, ALS is uniquely positioned among these conditions